Assessment of Protective Properties of Optimized Flagellin Derivative Against Biologically Harmful Effects of Ionizing Irradiation During Space Flight, Phase I

Metadata Updated: July 17, 2020

The goal of this proposal is to explore a novel proprietary biopharmaceutical agent, named deltaFL-AA', a first in the series of innovative radioprotectors to act as an agent providing protection of the organism against major space radiation risks. These risks include organism death resulting from acute irradiation as well as radiation-induced carcinogenesis caused by low-dose exposure. An unprecedented radioprotective potency of deltaFL-AA' demonstrated by its ability to cure 100% of mice from supralethal (14 Gy) doses of gamma-irradiation and its strong immunostimulatory properties (especially the ability to trigger natural killer response, which is well established as one of the antitumor firewalls) make this drug an extremely attractive candidate for testing in a NASA-funded program.

Access & Use Information

Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

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Dates

Metadata Created Date August 1, 2018
Metadata Updated Date July 17, 2020

Metadata Source

Harvested from NASA Data.json

Additional Metadata

Resource Type Dataset
Metadata Created Date August 1, 2018
Metadata Updated Date July 17, 2020
Publisher Space Technology Mission Directorate
Unique Identifier TECHPORT_10069
Maintainer
TECHPORT SUPPORT
Maintainer Email
Public Access Level public
Bureau Code 026:00
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Metadata Catalog ID https://data.nasa.gov/data.json
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id f22d0efd-bf5b-4264-97ab-0b323dd425a0
Harvest Source Id 39e4ad2a-47ca-4507-8258-852babd0fd99
Harvest Source Title NASA Data.json
Data First Published 2007-01-01
Homepage URL https://techport.nasa.gov/view/10069
Data Last Modified 2020-01-29
Program Code 026:027
Source Datajson Identifier True
Source Hash 517af70aeb6611bc26bf92e4a64917777f1ec7bd
Source Schema Version 1.1

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