The U.S. Geological Survey (USGS) National Water Quality Program (NWQP) provides an understanding of water-quality conditions; whether conditions are getting better or worse over time; and how natural features and human activities affect those conditions. The Surface Water Trends (SWT) project of NWQP evaluates the directions, periods, and statistical significance of trends in water quality in streams and rivers. This data release was generated for SWT and provides annual agricultural pesticide use (1992-2014) for selected watersheds where long-term water quality is measured and where subsequent trend analysis will be conducted. County-level pesticide use estimates for 33 compounds were allocated to agricultural land for 70 SWT watersheds.