A Robust, Cell-free Production System for On-Demand Protein Synthesis in Space

Metadata Updated: March 22, 2019

We will develop a new cell-free expression system that functions after rehydrating from a freeze-dried condition. Freeze-dried powder that can be stored or transported at room temperature with reduced volume and mass, thus decreasing mission risk and increasing flexibility in production. Recently D. radiodurans ultrafiltrate (extraction of low molecular size compounds < 3.5 kDa) has shown the capability of protecting freeze-dried enzymes from ionizing radiation suggesting that D. radiodurans cell-free lysate is most likely contains natural anti-oxidants[1]. No work has been reported on developing a cell-free expression system with extremophiles. We will to develop an extremely stable cell-free expression system using D. radiodurans cell lysate and evaluate the performance of protein expression after freeze-drying and rehydration

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Public: This dataset is intended for public access and use. License: U.S. Government Work

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Dates

Metadata Created Date August 1, 2018
Metadata Updated Date March 22, 2019

Metadata Source

Harvested from NASA Data.json

Additional Metadata

Resource Type Dataset
Metadata Created Date August 1, 2018
Metadata Updated Date March 22, 2019
Publisher Space Technology Mission Directorate
Unique Identifier TECHPORT_93219
Maintainer
TECHPORT SUPPORT
Maintainer Email
Public Access Level public
Bureau Code 026:00
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Metadata Catalog ID https://data.nasa.gov/data.json
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Datagov Dedupe Retained 20190322035503
Harvest Object Id 1d9379cf-775d-4dae-9bc9-466ee5ab5379
Harvest Source Id 39e4ad2a-47ca-4507-8258-852babd0fd99
Harvest Source Title NASA Data.json
Data First Published 2017-07-01
Homepage URL https://techport.nasa.gov/view/93219
License http://www.usa.gov/publicdomain/label/1.0/
Data Last Modified 2018-07-19
Program Code 026:027
Source Datajson Identifier True
Source Hash 94dda2248ff359c4f3ad9584760b7bd67fa539b6
Source Schema Version 1.1

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