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Federal
Transcriptional analysis of spleen from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
RAD51 Interconnects Between DNA Replication DNA Repair and Immunity
National Aeronautics and Space Administration —
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We... -
Federal
BRIC-21 Bacillus subtilis transcriptome profile data
National Aeronautics and Space Administration —
The BRIC-21 mission was designed to identify the response of Bacillus subtilis to the human spaceflight environment. For this mission samples were grown in rich-... -
Federal
International Space Station conditions alter genomics proteomics and metabolomics in Aspergillus nidulans
National Aeronautics and Space Administration —
The first global genomic proteomic and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse soleus muscle transcriptomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina
National Aeronautics and Space Administration —
The purpose of this study was to determine whether the spaceflight environment induces oxidative damage on ocular structure and how gene expression profiles change... -
Federal
Microbial Observatory (ISS-MO): Study of BSL-2 bacterial isolates from the International Space Station
National Aeronautics and Space Administration —
In an on-going Microbial Observatory experimental investigation on the International Space Station (ISS) multiple bacterial isolates of Biosafety Level 2 (BSL-2) were... -
Federal
Streptococcus mutans differential gene expression in response to simulated microgravity
National Aeronautics and Space Administration —
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host... -
Federal
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Kineosporiaceae bacterium B12 whole genome shotgun sequencing project
National Aeronautics and Space Administration —
Rubinsicoccus jplei genome a novel genus isolated from JPL spacecraft environment where Mars 2020 subsystems are assembled. -
Federal
Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice
National Aeronautics and Space Administration —
Spaceflight has been shown to suppress the adaptive immune response, altering the distribution and function of lymphocyte populations. B lymphocytes express highly... -
Federal
Mouse femur LC-MSMS upon weightlessness
National Aeronautics and Space Administration —
Bone loss and immune dysregulation are among the main adverse outcomes of spaceflight challenging astronaut xe2 x80 x99s health and safety. However consequences on B... -
Federal
Microbial Observatory (ISS-MO): Antimicrobial resistance genes
National Aeronautics and Space Administration —
The environmental samples were collected with the polyester wipes from eight different locations in the International Space Station (ISS) during two consecutive... -
Federal
Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols
National Aeronautics and Space Administration —
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a Rotating cell culture system to simulate microgravity and mRNA expression profile was observed in comparison to Static... -
Federal
Streptococcus mutans differential gene expression in response to simulated microgravity
National Aeronautics and Space Administration —
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Microbial Observatory (ISS-MO): Microbial diversity
National Aeronautics and Space Administration —
The environmental microbiome study was designed to decipher microbial diversity of the International Space Station surfaces in terms of spatial and temporal... -
Federal
Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue
National Aeronautics and Space Administration —
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological... -
Federal
ISS Bacillus Genomes
National Aeronautics and Space Administration —
SRA of spore forming Bacillus strains isolated from various areas of the ISS during Microbial tracking investigation