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Federal
The baboon (
U.S. Department of Health & Human Services —
Background As novel endovascular strategies are developed for treating neurological disease, there is an increasing need to evaluate these techniques in relevant... -
Federal
Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation
U.S. Department of Health & Human Services —
Background The peroxisome proliferator-activated receptor α (PPARα) plays an important role in the metabolism of lipoproteins and fatty acids, and seems to protect... -
Federal
Transcutaneous flow related variables measured in vivo: the effects of gender
U.S. Department of Health & Human Services —
Backgound The identification of potential sources of error is a crucial step for any new assessment technique. This is the case for transcutaneous variables, such as... -
Federal
Debate: Should statin be used in patients with heart failure?
U.S. Department of Health & Human Services —
Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the... -
Federal
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overload
U.S. Department of Health & Human Services —
Background Icodextrin is a high molecular weight, starch-derived glucose polymer, which is capable of inducing sustained ultrafiltration over prolonged (12–16 hour)... -
Federal
What is the optimal prophylaxis for treatment of cardiac allograft vasculopathy?
U.S. Department of Health & Human Services —
Coronary artery disease in the transplanted heart, also known as cardiac allograft vasculopathy (CAV), is one of the major causes of mortality late after... -
Federal
Is clopidogrel superior to aspirin in secondary prevention of vascular disease?
U.S. Department of Health & Human Services —
The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular... -
Federal
Lack of agreement between bioimpedance and continuous thermodilution measurement of cardiac output in intensive care unit patients
U.S. Department of Health & Human Services —
Background: Bolus thermodilution is the standard bedside method of cardiac output measurement in the intensive care unit (ICU). The Baxter Vigilance monitor uses a... -
Federal
Myocardial bridging as a cause of acute myocardial infarction: a case report
U.S. Department of Health & Human Services —
Background Systolic compression of a coronary artery by overlying myocardial tissue is termed myocardial bridging. Myocardial bridging usually has a benign prognosis,... -
Federal
Equipment review: Intrahospital transport of critically ill patients
U.S. Department of Health & Human Services —
Background This review on the current literature of the intrahospital transport of critically ill patients addresses type and incidence of adverse effects, risk... -
Federal
Cloning and expression of the rabbit prostaglandin EP2 receptor
U.S. Department of Health & Human Services —
Background Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence... -
Federal
Noninferiority trials
U.S. Department of Health & Human Services —
In one of the biggest dilemmas facing cardiovascular clinical research, clinical trials are increasingly being required to show benefits on clinical end-points rather... -
Federal
How hyperglycemia promotes atherosclerosis: molecular mechanisms
U.S. Department of Health & Human Services —
Both type I and type II diabetes are powerful and independent risk factors for coronary artery disease (CAD), stroke, and peripheral arterial disease. Atherosclerosis... -
Federal
Is age an independent determinant of mortality in cardiac surgery as suggested by the EuroSCORE?
U.S. Department of Health & Human Services —
Background The proportion of older patients in cardiac surgery is continuously increasing. 37% of patients undergoing heart surgery in Germany in the year 2000 were... -
Federal
Morphological, histochemical, and interstitial pressure changes in the tibialis anterior muscle before and after aortofemoral bypass in patients with peripheral arterial occlusive disease
U.S. Department of Health & Human Services —
Background Morphological and electrophysiological studies of ischemic muscles in peripheral arterial disease disclosed evidence of denervation and fibre atrophy. The... -
Federal
PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics
U.S. Department of Health & Human Services —
Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that... -
Federal
Simultaneous intra/extravascular administration of antiproliferative agents as a new strategy to inhibit restenosis: The peak of reactive cell proliferation as a hallmark for the duration of the treatment
U.S. Department of Health & Human Services —
Background Strictly intravascular approaches for the treatment of postangioplasty restenosis are effective in the intima and the inner parts of the media but may be... -
Federal
Implications of troponin testing in clinical medicine
U.S. Department of Health & Human Services —
During the past decade considerable research has been conducted into the use of cardiac troponins, their diagnostic capability and their potential to allow risk... -
Federal
Capgras syndrome: a clinical manifestation of watershed cerebral infarct complicating the use of extracorporeal membrane oxygenation
U.S. Department of Health & Human Services —
Ischaemic cerebral accidents are frequent following extracorporeal membrane oxygenation (ECMO), especially after fixing the reinjection cannula in the right primitive... -
Federal
Endovascular treatment of huge saccular abdominal aortic aneurysm in a young Behcet patient: mid-term result
U.S. Department of Health & Human Services —
Background Abdominal aortic aneurysm formation is among the arterial complications of Behcet's disease. Weakness and fragility of aortic walls leads to the...